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AIM HY

AIM HY

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Publications

  1. Zierer J, Pallister T, Tsai PC, Krumsiek J, Bell JT, Lauc G, Spector TD,Menni C, Kastenmüller G. Exploring the molecular basis of age-related disease comorbidities using a multi-omics graphical model. Sci Rep. 2016;6:3764-6. doi: 10.1038/srep37646.
  2. Menni C, Migaud M, Glastonbury CA, Beaumont M, Nikolaou A, Small KS, Brosnan MJ, Mohney RP, Spector TD, Valdes AM.Metabolomic profiling to dissect the role of visceral fat in cardiometabolic health. Obesity (Silver Spring). 2016;6:1380-8. doi: 10.1002/oby.21488.
  3. Boal AH, Smith DJ, McCallum L, Muir S, Touyz RM, Dominiczak AF, Padmanabhan S. Monotherapy with major antihypertensive drug classes and risk of hospital admissions for mood disorders. Hypertension 2016;68(5):1132-1138. DOI:10.1161/HYPERTENSIONAHA.116.08188
  4. Menni C, Metrustry S, Ehret G, Dominiczak AF, Chowienczyk P, Spector TD, Padmanabhan S, Valdes AM. Molecular pathways associated with blood pressure and hexadecanedioate levels. PLoS One.2017;12(4):e0175479. doi: 1371/journal.pone.0175479
  5. Menni C.Lessons on dietary biomarkers from twin studies. Proc Nutr Soc. 2017;76(3):303-307. doi: 10.1017/S0029665116002810.
  6. Menni C, Zierer J, Valdes AM, Spector TD.Mixing omics: combining genetics and metabolomics to study rheumatic diseases.  Nat Rev Rheumatol. 2017;13(3):174-181. doi: 10.1038/nrrheum.2017.5. Review.
  7. Menni C, Jackson MA, Pallister T, Steves CJ, Spector TD, Valdes AM.Gut microbiome diversity and high-fibre intake are related to lower long-term weight gain. Int J Obes (Lond). 2017;41(7):1099-1105. doi: 10.1038/ijo.2017.66.
  8. Vennin S, Li Y, Willemet M, Fok H, Gu H, Charlton P, Alastruey J, Chowienczyk P. Identifying haemodynamic determinants of pulse pressure: a combined numerical and physiological approach. 2017;70(6):1176-1182. doi: 10.1161/HYPERTENSIONAHA.117.09706.
  9. Menni C, Gudelj I, MacDonald-Dunlop E, Mangino M, Zierer J, Besić E, Joshi PK, Trbojević-Akmačić I, Chowienczyk PJ, Spector TD, Wilson JF, Lauc G, Valdes AM. Glycosylation profile of immunoglobulin g is cross-sectionally associated with cardiovascular disease risk score and subclinical atherosclerosis in two independent cohorts. Circ Res. 2018. pii: CIRCRESAHA.117.312174. doi: 10.1161/CIRCRESAHA.117.312174. [Epub ahead of print]

In press & under review

  1. Menni C, Lin C, Cecelja M, Mangino M, Matey-Hernandez ML, Keehn L, Mohney RP, Steves CJ, Spector TD, Kuo CF, Chowienczyk PJ, Valdes AM. Gut microbial diversity is associated with lower arterial stiffness in women. Circ Res. 2018; in press.
  2. Iniesta R, Campbell D, Venturini C, Singh S, Irvin MR, Cooper-DeHoff R, Johnson JA, Turner ST, Arnett DK, Weale M, Warren H, Munroe PB, Padmanbhan S, Lewis C, Chowienczyk PJ. Genetically defined ancestry as predictor of response to hypertensive treatment in ethnically admixed individuals. (in revision).
  3. Muktar O, Collier D, Padmanabhan S, Cheriyan J, Mander A, Mant J, Martin U, McEniery C, Cecelija M, Faconti L, Chowienczyk P, Sever P, Wilkinson I. Comparision of Optimal Hypertension Regimes (INFORM), Part of the Ancestry and Biological Information Markers for the Stratification of Hypertension (AIM HY) Programme. (in revision).
Share your comments on “your life with hypertension” and/or your experience of AIM HY INFORM Clinical Trial.

” I was diagnosed with high blood pressure more than 10 years ago. In August 2015, I had a Coronary Angioplasty surgery when three stents were inserted in one of my heart’s arteries. My symptoms improved a bit but not significantly. In August 2017, I saw an advert inviting people to participate in the AIM HY programme. I hurriedly offered myself as a guinea-pig. I have only started the first round of dual therapy and believe me, I am feeling so much better.

For the first time in many years, I ran to catch a bus without feeling short of breath. I have opted to be an ambassador of this programme because it is effective.

If you would like to leave a comment related to your treatment or the AIM HY INFORM trial experience, please click here. 

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