Work Strand 6

Interview with Prof. Phil Chowienczyk, Lead of the AIM HY Consortium and Dr Dike Ojji, Head of Cardiology Unit, Department of Internal Medicine at University of Abuja Teaching Hospital, African Collaborator on Comparison of Three Combination Therapies in Lowering Blood Pressure in Black Africans, CREOLE Clinical Trial.

Co-leads: Prof. Kennedy Cruickshank (King’s College London) and Prof. Charles Wolfe (King’s College London)

Photo of Prof. Kennedy Cruickshank — Prof. Kennedy Cruickshank

Photo of Professor Charles Wolfe — Prof. Kennedy Cruickshank

During the time course of this project we will use our links in the Caribbean and Africa to explore applying its outputs to Low and Middle income countries (LMIC) populations.

Creole study

In this arm of AIM HY study, we are taking advantage of the uniqueness of the data set that is being generated from the ‘The comparison of three combination therapies in lowering blood pressure in Black Africans’ (CREOLE) study to carry out genetic and phenotypic (including metabolomic) profiling with the ultimate goal of individualizing hypertension therapy in this population group.

We also intend to compare the data set generated in our population (Black Africans) and those generated in Europe and North America. CREOLE study is led by AIM HY collaborator, Dr Dike Ojji, Head of Cardiology Unit, Department of Internal Medicine, the University of Abuja Teaching Hospital, Nigeria