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Biostatistics

Work strand 2

Work strand 2 co-leads
  • Photo of Prof. Cathryn Lewis
    Prof. Cathryn Lewis
  • Photo of Dr Adrian Mander
    Dr Adrian Mander

AIM HY will generate large amounts of clinical, genetic and metabolomic data, which need sophisticated statistical analysis to ensure the research programme achieves its aims. Work Strand 2 will provide the necessary statistical methodology and analysis to support WS1, WS3 and subsequent work strands.

Statistical genetics work from Professor Cathryn Lewis and Dr Raquel Iniesta at KCL is being focused on using data from the existing US clinical trials to develop panels of Ancestry Informative Markers, and to test whether ancestry that is genetically defined is a better predictor of response than self-defined ethnicity.

The team will submit on early 2017 a scientific article about their last advances on this research. The biostatistics work from Dr Adrian Mander’s team at The MRC Biostatistics Unit aims to provide support to the design and analysis of the RCT in WS3, as well as the mechanistic and global WSs.

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THE PATIENT FORUM

Share your comments on “your life with hypertension” and/or your experience of AIM HY INFORM Clinical Trial.

“I was diagnosed with high blood pressure more than 10 years ago. In August 2015, I had a Coronary Angioplasty surgery when three stents were inserted in one of my heart’s arteries. My symptoms improved a bit but not significantly. In August 2017, I saw an advert inviting people to participate in the AIM HY programme. I hurriedly offered myself as a guinea-pig. I have only started the first round of dual therapy and believe me, I am feeling so much better.
For the first time in many years, I ran to catch a bus without feeling short of breath. I have opted to be an ambassador of this programme because it is effective.
I want as many people particularly from the ethnic minorities to benefit.”

“I recently did this study as a patient and I highly recommend it. Jane Smith is fantastic.”

If you would like to leave a comment related to your treatment or the AIM HY INFORM trial experience, please click here. 

Share your comments on “your life with hypertension” and/or your experience of AIM HY INFORM Clinical Trial.

” I was diagnosed with high blood pressure more than 10 years ago. In August 2015, I had a Coronary Angioplasty surgery when three stents were inserted in one of my heart’s arteries. My symptoms improved a bit but not significantly. In August 2017, I saw an advert inviting people to participate in the AIM HY programme. I hurriedly offered myself as a guinea-pig. I have only started the first round of dual therapy and believe me, I am feeling so much better.

For the first time in many years, I ran to catch a bus without feeling short of breath. I have opted to be an ambassador of this programme because it is effective.

If you would like to leave a comment related to your treatment or the AIM HY INFORM trial experience, please click here. 

The Consortium

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